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NJ Law Enables SUDC Research  
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The New Jersey Office of the State Medical Examiner in conjunction with the Department of Health and Senior Services and the Sudden Child Death Autopsy Protocol Committee has developed a protocol delineating required procedures for all medical research activities in the State of New Jersey involving medical examiners and duly approved and authorized research projects for the purpose of identifying potential causes of Sudden Infant Death Syndrome (SIDS) and Sudden Unexplained Death in Childhood (SUDC). All research projects must be submitted to the Office of the State Medical Examiner and approved prior to commencement of medical examiner participation in any proposed research project. A copy of the full protocol containing the details of the application process and the conduct of SIDS/SUDC research activities may be found on the State of New Jersey web site link here or by contacting the NJ Office of the State Medical Examiner at 609-896-8900.
Published Articles Relating to SUDC  
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Published Research Related to SUDC: 
 
Baker AM, Crandall L. To Hold Or Not To Hold. Forensic Sci Med Pathol. 2009 (Dec; 5(4):321-3. Epub 2009 Nov 13.  Balancing the needs of an investigation and the sensitive care of families is possible. Last year I co-authored an article on this topic with Dr. Andrew Baker which was published in the journal Forensic Science, Medicine and Pathology titled, "To Hold Or Not To Hold". You can also obtain the published article by visiting SpringerLink.  

Hannah C. Kinney, M.D., Amy E. Chadwick, B.A., Laura A. Crandall, M.A., Marjorie Grafe, M.D., Dawna L. Armstrong, M.D., William J. Kupsky, M.D., Felicia L. Trachtenberg, Ph.D., and Henry F. Krous, M.D. Sudden Death, Febrile Seizures, and Hippocampal and Temporal Lobe Maldevelopment in Toddlers: A New Entity Pediatr Dev Pathol 2009 Jul 16:1. Epub 2009 Jul 16
 
Krous HF, Wahl C, Chadwick AE. Sudden unexpected death in a toddler with Williams Syndrome. Forens Sci Med Pathol. In Press.

Kinney HC, Armstrong DL, Chadwick AE, et al. Sudden Death in Toddlers Associated with Developmental Abnormalities of the Hippocampus: a report of five cases. Pediatr Dev Pathol. 2007;10:208-223

Krous H, Chadwick A, Miller D, Crandall L, Kinney H. Sudden Death in Toddlers with Viral Meningitis, Massive Cerebral Edema, and Neurogenic Pulmonary Edema and Hemorrhage: Report of Two Cases. Pediatr Dev Pathol. 2007;10:463-469

Masoumi H, Kinney HC, Chadwick AE, Rubio A, Krous HF. Sudden unexpected death in childhood associated with cardiac rhabdomyoma, involuting adrenal ganglioneuroma, and megalencephaly: another expression of tuberous sclerosis? Pediatr Dev Pathol. 2007;10:129-133.

Krous HF, Chadwick AE, Crandall L, Nadeau-Manning. Sudden Unexpected Death In Childhood: A Report of 50 Cases. Pediatric Dev Pathol. 2005;8:307-319

Wixom C, Krous HF, Chadwick AE. Sudden, Unexpected Death Associated with Meningioangiomatosis. Pediatr Dev Pathol. 2005;8:240-244

Kinney H, Armstrong DL, Chadwick AE, Crandall L, Hilbert C, Krous H. Abstract: Seizures, Cerebral Edema and Hippocampal Anomolies in Sudden Unexplained Death In Childhood (SUDC): Report of A Series. J Neuropathol Exp Neurology 2004; 63 (5):556

Beckwith JB. The sudden infant death syndrome. Curr Probl Pediatr 1973;3(8):1-36.

Southall DP, Stebbens V, Shinebourne EA. Sudden and unexpected death between 1 and 5 years. Arch Dis Child 1987;62(7):700-5.

Helweg-Larsen K, Garde E. Sudden natural death in childhood. A review of forensic autopsy protocols in cases of sudden death between the ages of one and five years, 1982-1991, with a special view to sudden unexplained death. Acta Paediatr 1993;82(11):975-8.

Molander N. Sudden natural death in later childhood and adolescence. Arch Dis Child 1982;57(8):572-6.

Neuspiel DR, Kuller LH. Sudden and unexpected natural death in childhood and adolescence. Jama 1985;254(10):1321-5.

Siboni A, Simonsen J. Sudden unexpected natural death in young persons. Forensic Sci Int 1986;31(3):159-66.

Keeling JW, Knowles SA. Sudden death in childhood and adolescence. J Pathol 1989;159(3):221-4.

Norman MG, Taylor GP, Clarke LA. Sudden, unexpected, natural death in childhood. Pediatr Pathol 1990;10(5):769-84.

Morentin B, Aguilera B, Garamendi PM, Suarez-Mier MP. Sudden unexpected non-violent death between 1 and 19 years in north Spain. Arch Dis Child. 2000 Jun;82(6):456-61.

References for Channelopathies:

Ackerman MJ, Tester DJ, Driscoll, DJ. Molecular autopsy of sudden unexplained death in the young. The American Journal of Forensic Medicine and Pathology. 2001; 22(2): 105-111.

Ackerman MJ, Khosiseth A, Tester DJ, Hejlik J, Shen WK, Porter CJ. Epinephrine-induced QT interval prolongation: a gene-specific paradoxical response in congenital long QT syndrome. Mayo Clinic Proceedings. 2002;77:413-421.

Baruteau AE, Baruteau J, Joomye R, Martins R, Treguer F, Baruteau R,
Daubert JC, Mabo P, Roussey M Role of congenital long-QT syndrome in unexplained sudden infant death: proposal for an electrocardiographic screening in relatives
Eur J Pediatr. 2009 Mar 6 [Epub ahead of print]

References for metabolic disease and evaluation:

Rinaldo P, Matern D, Bennett MJ. Fatty acid oxidation disorders. Ann Rev Physiol 64:16.1-26, 2002.

Bennett MJ, Rinaldo P. The Metabolic Autopsy comes of Age. Clinical
Chemistry 47; 1145-6, 2001

Rinaldo P, Yoon HR, Yu C, Raymond K, Tiozzo C, Giordano G. (1999) Sudden and unexpected neonatal death: A protocol for the postmortem diagnosis of fatty acid oxidation disorders. Sem Perinatol 23:204-210


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